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Anne Rice , the second daughter in a Catholic Irish-American family. Her works have had a major influence on the "Goth" movement, and she has also published a number of works with sado-masochistic themes. She was married to the late poet Stan Rice and is the mother of novelist Christopher Rice. Her daughter, Michele, was born on September 21, 1966 and died of leukemia on August 5, 1972. Anne's sister, Alice Borchardt, is also a noted genre author.

Rice was born and spent most of her life in New Orleans, Louisiana, the city that forms the background against which most of her stories take place. Known for her avid interest in art and culture, she and her family occasionally took trips overseas to study the art later mentioned in her stories. More recently, following the death of her husband Stan Rice, she has relocated to the Coachella Valley, California area to be nearer her son, Christopher. After spending most of her adult life as a self described atheist, Rice returned to the Roman Catholic Church in 1998, and she is currently working on a trilogy about the life of Jesus.

Rice has also published erotica under the pen names , the latter of which was used primarily for more adult-oriented material. Her fiction is often described as lush and deive, and her characters' sexuality is fluid, often displaying homoerotic feelings towards each other. She also deals with philosophical and historic themes, weaving them in to the dense pattern of her books, and giving them a highly intellectual, if not highly literary, content. To her admirers, Rice's books are among the best in modern popular fiction, considered by some to possess those elements that create a lasting presence in the literary canon. To her critics, her novels are baroque, "low-brow pulp" and redundant.

A critical analysis of Rice's work can be found in S. T. Joshi's book

In October of 2005, Rice announced in a Newsweek article that she would "write only for the Lord". Her first novel in the genre is called can also be viewed as an example of psychedelic literature. Rice herself has denied ever having experimented with LSD. "I'm a totally conservative person. In the middle of Haight-Ashbury in the 1960s, I was typing away while everyened awareness after being transformed into a vampire which does mirror the LSD experience to some extent.

Rice has said that Claudia, the young girl in the book, was inspired by her late daughter.

In 1994, Neil Jordan directed a motion picture adaption of Interview with the Vampire, based on the story, but with some minor changes. A second movie was later made, inspired by the second and third books in the original . The storyline chosen by the producers of the second film is controversial among many fans of her books. Major plot points of both books were altered, and it has been rumoured that the second film's theatrical release was based solely on its producers' wish to capitalize on the death of Aaliyah. Another rumor being that Warner Bros. was already into its last year of owning motion picture rights to the first three Vampire Chronicles books, which would then have transferred back to author Anne Rice once this period was over. Once back in her ownership, she could then sell the rights to another company of her choosing. Knowing what little time they had left, despite the fact they've had the rights and opportunity to make the latter two movies for over seven years, Warner Bros. hastily hired writers to condense the books " based loosely on Rice's book of the same name starred Rosie O'Donnell and Dan Aykroyd. The plot was seriously altered, with the work transformed from a love story into a police comedy, possibly due to the explicit S

Rice has Type 1 diabetes. This was discovered when she went into a diabetic coma in December of 1998. She is an advocate for people to get tested for diabetes. Because of a lifelong battle with her weight as well as depression due to the long illness and subsequent death of her husband, Rice's weight ballooned to 254 pounds. Tired of dealing with sleep apnea, limited mobility, and other weight-related problems, she had gastric bypass surgery on January 15, 2003.

On 30 January 2004 Rice announced her plans to leave New Orleans to move the suburb of Jefferson Parish, Louisiana. She had already put the largest of her three homes in Uptown New Orleans up for sale, and plans to sell the other two. She cited living alone since the death of her husband and her son's moving out of state as the reasons. "Simplifying my life, not owning so much, that's the chief goal," said Rice. "I'll no longer be a citizen of New Orleans in the true sense." In spring 2005 Anne Rice moved to La Jolla, California. She calls her new home "Paradise West." Some have speculated that Rice also wished for more privacy from the constant attentions of her fans, who were known to camp out in front of her house. Sometimes, up to 200 or more would gather to see her leave for church on Sundays. She is also very adamant about preventing any fan fiction of her books-- on April 7, 2000, she released a statement on her website that prohibited all fanfiction involving her work. This caused the removal of thousands of fanfics from the popular Fanfiction.Net website.

On September 6, 2004, Rice posted a reply to a number of negative reviews that had appeared on Amazon.com regarding . She titled her reply, "From the Author to the Some of the Negative Voices Here." This post generated a great deal of publicity online -- partly because authors rarely post or respond to reviews on Amazon, and partly because of the tone and nature of her text. Many previous reviews had criticized the quality of writing in as lazy or shoddy; so when Rice replied by posting a 1,200-word paragraph wherein she proudly dismisses the utility of editors, the incident became fodder for weblogs and Internet sites.