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Vince Edwards in Brooklyn, New York, he was a star of his high school swim team who went on to study at Ohio State University on an athletic scholarship. There, he was part of the university's swim team that won the United States National Championships.

Zoino studied acting at the American Academy of Dramatic Arts and in 1950 he was signed to a contract by Paramount Pictures, making his film debut as "Vince Edwards" in 1951's " television series that he achieved a real level of stardom. The medical drama show, which he occasionally directed, ran from 1961 to 1966 and as a result of his popularity, Edwards released several music albums that met with reasonable success.

When the television series ended, Edwards returned to acting in motion pictures with a major role in the 1968 war drama, . He continued to act in film as well as in guest spots on television plus he directed a number of episodes in a variety of television series.

Vince Edwards made his last film in 1995 after which he was diagnosed with pancreatic cancer. He passed away in Los Angeles, California the following year and was interred in the Holy Cross Cemetery in Culver City, California.